Hydrea (Hydroxyurea) 500 Mg 100 Capsules

Adjuncts: Citric acid anhydride, sodium phosphate bibasic anhydride, magnesium stearate,
lactose, gelatin, erythrocin (E127), indigotine (E132), titanium dioxide (E171), yellow iron oxide
(E172), sodium lauryl sulfate

Before starting to use this medication, carefully read this USE INSTRUCTION
because it contains important information for you.

· Save these instructions for use. You can need to read again.
· If you have other questions, please talk your doctor or pharmacist.
· This medication is prescribed for you personally, do not give it to others.
· During the use of this medicine, if you go to a doctor or a hospital, you
tell them you are using medicine.
· We sleep exactly as written in this instruction. The recommended dosage for your medication
Do not use high or low dose.
In this Instructions for Use:

1. What is HYDREA and what is it used for?
2. Things to watch out for before using HYDREA
3. How to use HyDREA?
4. What are the possible side effects?
5. Storage of HYDREA
Their headlines are in place.

1. What is HYDREA and what is it used for?
HYDREA capsule, consisting of two parts with green cover with "BMS 300" printed and pink opaque body
In the hard gelatin capsules are white powder.
HYDREA 500 mg Capsules are available in 100 capsule capsules. One in each box
There is a sise.
HYDREA, a drug called antineoplastics and used in the treatment of cancer
It is from the group.
HYDREA in the treatment of some cancer diseases such as cervical cancer, chronic myelocytic
in the treatment of cancer of a type of blood cells called leukemia and in the treatment of sickle cell anemia
anemia) treatment.
Consult your doctor to find out more clearly why you are using HYDREA.

2. Things to watch out for before using HYDREA
DO NOT USE HYDREA in the following situations
Do not use if you have allergies to hydroxyurea or other components of the drug.
Do not use if you are pregnant or if you are planning to become pregnant or breast-feeding.
HYDREA ARE USING ATTENTION
If,
· If you have any blood disease,
· If you have a problem with your kidney,
· If you have Gout (drip disease) disease,
· If you are taking a drug against HIV (human immunodeficiency virus)
· If you are currently taking any medication for cancer treatment, especially interferon treatment
If you receive
If these warnings are valid for you at any time in the past, please
you consult your doctor.
Use of HYDREA with food and drink
HYDREA has no interaction with food and beverages. While being treated with HYDREA
drink plenty of fluids for your kidneys to work well. Alcohol under treatment
consult your doctor about its use.
Pregnancy
You should consult your doctor or pharmacist before using the medicine.
· If you are pregnant or plan to become pregnant, but your doctor
you can use HYDREA.
· Avoid becoming pregnant during treatment with HYDREA and an effective contraceptive
method. Otherwise your baby may be harmed by the medicine.
If you notice that you are pregnant during your treatment, your doctor or pharmacist
Your consultant.

Breast-feeding
You should consult your doctor or pharmacist before using the medicine.
Do not breast-feed your baby while you are being treated because HYDREA has passed away.
Vehicle and machine use
HYDREA can cause you to feel sleepy. If you do not consult your doctor with any
Do not use the machine.

Important information about some of the auxiliary substances contained in HYDREA
Due to the lactose present in your body,
If you are told that you have intolerance (intolerance), before you get HYDREA
go to the doctor with your doctor.
Use with other medicines:
Taking some medications with HYDREA may require dose adjustment.
if,
· If you are using drugs that lower blood uric acid level (uricosuric)
· If you are taking medications that suppress bone marrow or warmth treatment
If you are taking cytarabine (a drug used in the treatment of cancer)
Please inform.
If you have any medications, or if you have recently
please inform your doctor or pharmacist about these.

3. How to use HyDREA?
Instructions for proper use and dose / application frequency:
Always use HYDREA on the side of your doctor tells you. If you are unsure
your doctor or pharmacist is definitely your consultant.
The recommended dose is 20-30 milligrams per kilogram of your body weight.
80 milligrams per kilogram of body weight per day should be calculated.

Sickle Cell Anemia:
The recommended dose is 15 milligrams per kilogram of body weight once a day.
Depending on your body weight and blood values, your doctor will start with HYDREA
dosa. The dose should then be the best you can tolerate
dose (the highest dose that does not cause a serious drop in blood values).
After you start treatment with HYDREA, your doctor will check your blood values ​​at regular intervals
you will. Depending on the results, your dose may be changed or a period of time for HYDREA treatment
Mentioned.
If you are seeing heat therapy, you should take HYDREA 7 days before the heat treatment
You should receive.
Application path and method:
Capsules are taken in sufficient quantities with water. If you can not swallow the capsules,
You can also get it out of the glass and drink immediately. Some fillers in the capsule
it may remain on the surface without being dissolved in water, so do not worry about it.
Breathe in the capsule contents. If dust comes in contact with your skin, wipe it off immediately.
Different age groups

Use in children:
The safety and efficacy of HYDREA in patients under 18 years of age has not been determined.
Use in ages:
Older patients may be more susceptible to the effects of HYDREA,
they may need to use.
Special use cases
Kidney / Liver failure:
If you have kidney or liver failure, your doctor's initial dose of HYDREA
and your blood values ​​should be closely monitored.
If you have an impression that the effect of HYDREA is too strong or weak
talk to your doctor or pharmacist.
If you use HYDREA than you need:
You should contact your doctor immediately if you use HYDREA than necessary, or
You should apply to the nearest hospital. Show your medicine box.
If you use HYDREA from a doctor or pharmacist
You talk.
If you forget to use HYDREA
If you forget to use HYDREA, skip the forgetfulness and do
Keep taking your doses.
Do not take double doses to compensate for forgotten doses.
Possible effects of treatment with HYDREA:
HYDREA usually takes six weeks after you start using it. your doctor
he will tell you how long your treatment will last. Even if you feel good, your doctor
Do not interrupt treatment early without consulting.
If you have any other questions about this medicine, you should consult your doctor or pharmacist.

4. What are the possible side effects?
Like all medicines, HYDREA is susceptible to substances present in the contents of the side
there may be effects.
If any of the following happens, stop using HYDREA and DERHAL
please contact your doctor or the emergency department of your nearest hospital:
- Money transfer (seizure)
- Skin cancer
- unexpected difficulty breathing or coughing with fever
These are all very serious side effects.

If any of these are present to you, you must not be placed in an emergency medical intervention or hospital
it may be necessary.
All of these very serious side effects are very rare.
If you notice any of the following, tell your doctor immediately or contact
contact the emergency department of your nearest hospital:

- Waist or flank pain
- Black, dark colored dots or whiskey blood
- Normal external bleeding or lacerations
- Unexplained fever, headache or sore throat
- numbness or tingling in hands or feet
- Skin ulcers, especially with serious inflammation
- Anemia
- Hallucinations (hearing, seeing or feeling things that are not)
All these are serious side effects. Immediate medical attention may be required.
Serious side effects are very rare.
If you notice any of the following, tell your doctor:

- Intolerance
- weakness or loss of energy
- Nausea, vomiting, diarrhea
- Constipation, indigestion, digestive disorders
- Headache
- Drowsiness, drowsiness
- Stupidness
- Wounds in the mouth or lip
- Temporary hair loss
- Rash
- Darkness in deep color
- Skin and nail loss
- Deep purple injuries or peeling
- Abdominal pain
- The problem of compatibility with the environment (disorientation)
- Flicker
- Deep frying after heat treatment
- difficult or painful urine

These are the minor side effects of HYDREA.
If you encounter any side effects not mentioned in these instructions for use
inform your doctor or pharmacist.

5. HYDREA Hiding
Store HYDREA in places where children can not be seen, where they can not be reached and in their packaging.
Store at room temperature below 25 ° C. Pregnant or planning to become pregnant
it should not contact the drug. Capsules should not be hot or humid. Therefore
Do not leave your medicine in front of the window or in the bathroom next to heaters such as radiators.
Close the sisenin cover tightly.
Use in accordance with expiration dates.
After the expiration date on the label or on the packaging, remove HYDREA
Do not use.
"Expiration Date" is the last day of the specified month.
Do not use HYDREA unless you notice any defects in the product and / or packaging.